Biennial, perennial or sometimes annual, succulent herbs. Leaves usually opposite and decussate, connate at the base, the lower set close together; uppermost bract-like; lamina entire or rarely pinnatifid; margin entire, crenate or serrate. Inflorescence terminal, composed of cymes arranged in a panicle, corymb or thyrse. Flowers 4-merous, erect, relatively large and showy. Corolla lobes united below into a tetragonous tube, this rounded and swollen at the base and usually constricted above; lobes usually apiculate. Stamens 8. Carpels 4, ± connate at base. Nectariferous scales semi-circular to linear. Worldwide: 125 species (incl. Bryophyllum) in the Old World tropics, especially Africa and Madagascar. Botswana: 5 taxa. Insects associated with this genus:
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| Species | FZ divisions | Content |
| brachyloba Welw. ex Britten | N,SE | Image |
| lanceolata (Forssk.) Pers. | N,SW,SE | Description, Image |
| paniculata Harv. | ||
| rotundifolia (Haw.) Haw. | SE | Description, Image |
| thyrsiflora Harv. | SE |